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2024

132. Han K, Xie F, Animasahun O, Nenwani M, Kitamoto S, Kim Y, Phoo MT, Xu J, Wuchu F, Omoloja K, Achreja A, Choppara S, Li Z, Gong W, Cho YS, Dobson H, Ahn J, Zhou X, Huang X, An X, Kim A, Xu Y, Wu Q, Lee SH, O’Konek JJ, Xie Y, Lei YL, Kamada N, Nagrath D, Moon JJ§. Inulin-gel-based oral immunotherapy remodels the small intestinal microbiome and suppresses food allergy. doi: 10.1038/s41563-024-01909-w, 2024. Nature Materials. Link PDF
**Featured by WXYZ 7 News Detroit and Michigan News.

131. Sun S, Zhou X, Shi X, Abed OA, An X, Lei YL, Moon JJ§. Strategies for the development of metalloimmunotherapies. doi: 10.1038/s41551-024-01221-7, 2024. Nature Biomedical Engineering. Link PDF

130. Nam J, Kim A, Kim K, Moon JH, Baig J, Phoo M, Moon JJ§, Son S§. Engineered polysaccharides for controlling innate and adaptive immune responses. Jun 18:1-9, 2024. Nature Reviews Bioengineering. Link PDF

129. Cho YS, Han K, Xu J, Moon JJ§, Novel strategies for modulating the gut microbiome for cancer therapy. May 15:115332 2024, Advanced Drug Delivery Reviews. Link PDF

128. Sun X, Huang X, Park KS, Zhou X, Kennedy AA, Pretto CD, Wu Q, Wan Z, Xu Y, Gong W, Sexton JZ, Tai AW, Lei YL, Moon JJ§. Self-Assembled STING-Activating Coordination Nanoparticles for Cancer Immunotherapy and Vaccine Applications. 2024, ACS NanoLink PDF

127. Aikins ME, Sun X, Dobson H, Zhou X, Xu Y, Lei YL, Moon JJ§. STING-activating cyclic dinucleotide-manganese nanoparticles evoke robust immunity against acute myeloid leukemia. 368, 768-779, 2024, Journal of Controlled ReleaseLink PDF

126. Jang Y*, Cho YS*, Kim A, Zhou X, Kim Y, Wan Z, Moon JJ§, Park H§. CXCR4-Targeted Macrophage-Derived Biomimetic Hybrid Vesicle Nanoplatform for Enhanced Cancer Therapy through Codelivery of Manganese and Doxorubicin. 16, 14, 17129-17144, 2024, ACS Applied Materials and InterfacesLink PDF

125. Shinn J, Park S, Lee S, Park N, Kim S, Hwang S, Moon JJ, Kwon Y, Lee Y. Antioxidative Hyaluronic Acid-Bilirubin Nanomedicine Targeting Activated Hepatic Stellate Cells for Anti-Hepatic-Fibrosis Therapy. 18, 6, 4704-4716, 2024, ACS NanoLink PDF

124. Han K*§, Xu J*, Xie F*, Crowther J, Moon JJ§. Engineering strategies to modulate the gut microbiome and immune system. 212, 2, 208-215, 2024, Journal of ImmunologyLink PDF

2023

123. Kim A*, Xie F*, Abed OA, Moon JJ§. Vaccines for immune tolerance against autoimmune disease. 203, 2023, Advanced Drug Delivery ReviewsLink PDF

122. Han K*, Cho YS*, Moon JJ. Antibiotic nanoparticles boost antitumor immunity. 2023, Nature BiotechnologyLink PDF

121. Lee Y§, Shinn J, Xu C, Dobson HE, Neamati N, Moon JJ§. Hyaluronic acid-bilirubin nanomedicine-based combination chemoimmunotherapy. 14, 4771, 2023, Nature CommunicationsLink PDF

120. Sun X, Zhou X, Lei YL, Moon JJ. Unlocking the promise of systemic STING agonist for cancer immunotherapy. 357, 417-421, 2023. Journal of Controlled ReleaseLink PDF

119. Jang Y, Kim A, Moon JJ, Lee JY, Park H. Novel bioengineering strategies for drug delivery systems. 1, 33, 101834, 2023.  Applied MaterialsLink PDF

118. Pearson RM, Acharya AP, Moon JJ. Emerging immunotherapeutics for immune activation and tolerance. doi: 10.1007/s13346-023-01352-5, 2023. Drug Deliv Transl Res. (Editorial) Link PDF

117.  Xu C, Dobson HE, Yu M, Gong W, Sun X, Park KS, Kennedy A, Zhou X, Xu J, Xu Y, Tai AW, Lei YL, Moon JJ. STING agonist-loaded mesoporous manganese-silica nanoparticles for vaccine applications. 357, 84-93, 2023, Journal of Controlled ReleaseLink PDF

116.  Saud KT*§, Xu J*, Wilkanowicz S, He Y, Moon JJ, Solomon MJ§. Electrosprayed microparticles from inulin and poly (vinyl) alcohol for colon targeted delivery of prebiotics. 140, 108625, 2023, Food Hydrocolloids. Link PDF

115. Son S§*, Nam J*, Kim AS, Ahn J, Park KS, Phoo MT, Sherren B, Zou W, Lee SH, Farokhzad OC, Shi J, Moon JJ§. Induction of T-helper-17-cell-mediated antitumour immunity by pathogen-mimicking polymer nanoparticles. 7, 1, 72-84, 2023, Nature Biomedical Eng. Link PDF
** Featured by Nat. Biomed. Eng News and Views, 7, 6–7, 2023.

114.  Heath BR, Gong W, Taner HF, Broses L, Okuyama K, Cheng W, Jin M, Fitzsimonds ZR, Manousidaki A, Wu Y, Zhang S, Wen H, Chinn SB, Bartee E, Xie Y, Moon JJ, Lei YL. Saturated fatty acids dampen the immunogenicity of cancer by suppressing STING. 42, 4, 112303, 2023, Cell Reports. Link PDF

2022

113. Aikins ME*, Qin Y*, Dobson HE*, Najafabadi AH, Lyu K, Yu Y, Xin Y, Schwendeman A, Wicha M, Chang AE, Li Q§, Moon JJ§. Cancer stem cell antigen nanodisc cocktail elicits anti-tumor immune responses in melanoma, 351, 872-882, 2022, Journal of Controlled Release. Link PDF

112. Okeke EB§, Louttit C, Snyder CM, Moon JJ§. Neutrophils and neutrophil extracellular traps in cancer: promising targets for engineered nanomaterials. Epub 20221002. 2022, Drug Deliv Transl ResLink PDF

111. Chan JF, Oh YJ, Yuan S, Chu H, Yeung ML, Canena D, Chan CC, Poon VK, Chan CC, Zhang AJ, Cai JP, Ye ZW, Wen L, Yuen TT, Chik KK, Shuai H, Wang Y, Hou Y, Luo C, Chan WM, Qin Z, Sit KY, Au WK, Legendre M, Zhu R, Hain L, Seferovic H, Tampe R, To KK, Chan KH, Thomas DG, Klausberger M, Xu C, Moon JJ, Stadlmann J, Penninger JM, Oostenbrink C, Hinterdorfer P, Yuen KY, Markovitz DM. A molecularly engineered, broad-spectrum anti-coronavirus lectin inhibits SARS-CoV-2 and MERS-CoV infection in vivo. 100774, 2022, Cell Rep Med. Link PDF

110. Abed OA*, Attlassy Y*, Xu J, Han K, Moon JJ§. Emerging Nanotechnologies and Microbiome Engineering for the Treatment of Inflammatory Bowel Disease. https://doi.org/10.1021/acs.molpharmaceut.2c00222, 2022, Molecular Pharmaceutics. Link PDF

109. Liao F, Zhang J, Hu Y, Najafabadi AH, Moon JJ, Wicha MS, Kaspo B, Whitfield J, Chang AE, Li Q. Efficacy of an ALDH peptide-based dendritic cell vaccine targeting cancer stem cells. doi: 10.1007/s00262-021-03129-6, 2022, Cancer Immunol Immunotherapy. Link PDF

108. Ahn J, Arai Y, Kim BJ, Seo YK, Moon JJ, Shin DA, Choi, B, Lee SH. Combinatorial physicochemical stimuli in the three-dimensional environment of a hyaluronic acid hydrogel amplify chondrogenesis by stimulating phosphorylation of the Smad and MAPK signaling pathways. 14, 46, 2022, NPG Asia Materials. Link PDF

2021

107. Schardt JS, Pornnoppadol G, Desai AA, Park KS, Zupancic JM, Makowski EK, Smith MD, Chen H, Garcia de Mattos Barbosa M, Cascalho M, Lanigan TM, Moon JJ, Tessier PM. Discovery and characterization of high-affinity, potent SARS-CoV-2 neutralizing antibodies via single B cell screening. 11, 1, 1-16, 2021, Scientific Reports. Link PDF

106. Garcia-Fabiani MB, Haase S, Comba A, Carney S, McClellan B, Banerjee K, Alghamri MS, Syed F, Kadiyala P, Nunez FJ, Candolfi M, Asad A, Gonzalez N, Aikins ME, Schwendeman A, Moon JJ, Lowenstein PR, Castro MG. Genetic Alterations in Gliomas Remodel the Tumor Immune Microenvironment and Impact Immune-Mediated Therapies. 11: 631037, 2021, Front Oncol. Link PDF

105. Li G, Kryczek I, Nam J, Li X, Li S, Li J, Wei S, Grove S, Vatan L, Zhou J, Du W, Lin H, Wang T, Subramanian C, Moon JJ, Cieslik M, Cohen M, Zou W. LIMIT is an immunogenic lncRNA in cancer immunity and immunotherapy, 23, 526-537, 2021, Nat. Cell Biol. Link PDF

104. Lee Y§, Kamada N, Moon JJ§. Oral nanomedicine for modulating immunity, intestinal barrier functions, and gut microbiome. 114021 2021, Advanced Drug Delivery Review. Link PDF

103. Sun X, Zhang Y, Li J, Park KS, Han K, Zhou X, Xu Y, Nam J, Xu J, Shi X, Wei L, Lei YL, Moon JJ§. Amplifying STING Activation by Cyclic Dinucleotide-Manganese Particles for Local and Systemic Cancer Metalloimmunotherapy. doi.org/10.1038/s41565-021-00962-9 , 2021, Nature Nanotech. Link PDF

102. Han K, Nam J, Xu J, Sun X, Huang X, Animasahun O, Achreja A, Joen JH, Pursley B, Kamada N, Chen GY, Nagrath D, Moon JJ§. Generation of systemic antitumour immunity via the in situ modulation of the gut microbiome by an orally administered inulin gel. doi: 10.1038/s41551-021-00749-2, 2021, Nature Biomedical Eng. Link PDF

101. Najafabadi AH, Abadi ZI, Aikins ME, Foulds KE, Donaldson MM, Yuan W, Okeke EB, Nam J, Xu Y, Weerappuli P, Hetrick T, Adams D, Lester PA, Salazar AM, Barouch DH, Schwendeman A, Seder RA, Moon JJ§. Vaccine nanodiscs plus polyICLC elicit robust CD8 T cell responses in mice and non-human primates. 337, 168-178, 2021, Journal of Controlled Release. Link PDF

100. Moon JJ§, De Geest B, Sun X. Next Generation Immunotherapies – Emerging Strategies for Immune Modulation against Cancer, Infections, and Beyond. doi.org/10.1002/adtp.202100157, 2021, Advanced Therapeutics. (Editorial) Link PDF

99. Nam J, Son S, Park KS, Moon JJ§. Photothermal therapy combined with neoantigen cancer vaccination for effective immunotherapy against large established tumors and distant metastasis. 2100093, 2021, Advanced Therapeutics. Link PDF

98. Park KS*, Nam J*, Son S, Moon JJ§. Personalized combination nano-immunotherapy for robust induction and tumor infiltration of CD8+ T cells, 274, 120844, 2021, Biomaterials. Link PDF

97. Alghamri MS, McClellan BL, Hartlage MS, Haase S, Faisal SM, Thalla R, Dabaja A, Banerjee K, Carney SV, Mujeeb AA, Olin MR, Moon JJ, Schwendeman A, Lowenstein PR, Castro MG. Targeting Neuroinflammation in Brain Cancer: Uncovering Mechanisms, Pharmacological Targets, and Neuropharmaceutical Developments. 12:680021, 2021, Front. Pharmacology. Link PDF

96. Park KS, Sun X, Aikins ME, Moon JJ§. Non-viral COVID-19 vaccine delivery systems, 169, 137-151, 2021, Advanced Drug Delivery Reviews. Link PDF

95. Nam J, Son S, Park KS, Moon JJ§. Modularly programmable nanoparticle vaccine based on polyethyleneimine for personalized cancer immunotherapy, 8, 5:2002577, 2021, Advanced Science. Link PDF

94. Arai Y, Choi B, Kim BJ, Park S, Park H, Moon JJ, Lee SH. Cryptic ligand on collagen matrix unveiled by MMP13 accelerates bone tissue regeneration via MMP13/Integrin α3/RUNX2 feedback loop, S1742-7061, 21, 00137-9, 2021, Acta Bio. Link PDF

93. Yuan W, Yu B, Yu M, Kuai R, Morin EE, Wang H, Hu D, Zhang J, Moon JJ, Chen YE, Guo Y, Schwendeman A. Synthetic high-density lipoproteins delivering liver X receptor agonist prevent atherogenesis by enhancing reverse cholesterol transport. 329:361-371, 2021, Journal of Controlled ReleaseLink PDF

92. Park KS, Bazzill JD, Son S, Nam J, Shin SW, Ochyl LJ, Meagher JL, Chang L, Stuckey JA, Song J, Montefiori DC, LaBranche CC, Smith JL, Xu J, Moon JJ§. Lipid-based vaccine nanoparticles for induction of humoral immune responses against HIV-1 and SARS-CoV-2. 330:529-539, 2021, Journal of Controlled ReleaseLink PDF

2020

91. Kadiyala P, Carney SV, Gauss JC, Garcia-Fabiani MB, Haase S, Alghamri MS, Núñez FJ, Liu Y, Yu M, Taher AW, Nunez FM, Li D, Edwards MB, Kleer CG, Appelman H, Sun Y, Zhao L, Moon JJ, Schwendeman A, Lowenstein PR, Castro MG. Inhibition of 2-Hydroxyglutarate Elicits Metabolic-reprograming and Mutant IDH1 Glioma Immunity in Mice. 131, 4, e139542, 2020, Journal of Clinical Investigation. Link PDF

90. Chen XS, Moon JJ, Cheon J. New Opportunities in Cancer Immunotherapy and Theranostics. 53, 12:2763-2764, 2020, Accounts of Chemical Research. (Editorial) Link PDF

89. Aikins MEXu C, Moon JJ§. Engineered Nanoparticles for Cancer Vaccination and Immunotherapy. doi.org/10.1021/acs.accounts.0c00456, 2020, Accounts of Chemical ResearchLink PDF

88. Zhou X, Jing X, Qu, M, Aninwene GE, Jacaud V, Moon JJ, Gu Z, Sun W, Khademhosseini A. Engineering Antiviral Vaccines. doi.org/10.1021/acsnano.0c06109, 2020, ACS NanoLink PDF

87. Xu C, Hong H, Lee Y, Park KS, Sun M, Wang T, Aikins ME, Xu Y, Moon JJ§. Efficient Lymph Node-Targeted Delivery of Personalized Cancer Vaccines with Reactive Oxygen Species-Inducing Reduced Graphene Oxide Nanosheets. doi.org/10.1021/acsnano.0c05062, 2020, ACS NanoLink PDF

86. Hassani Najafabadi A*, Zhang J*, Aikins ME, Najaf Abadi ZI, Liao F, Qin Y, Okeke EB, Scheetz LM, Nam J, Xu Y, Adams D, Lester P, Hetrick T, Schwendeman A, Wicha MS, Chang AE, Li Q§, Moon JJ§. Cancer Immunotherapy via Targeting Cancer Stem Cells Using Vaccine Nanodiscs. doi.org/10.1021/acs.nanolett.0c03414, 2020, Nano LettersLink PDF

85. Park KS, Xu C, Sun X, Louttit C, Moon JJ§. Improving STING Agonist Delivery for Cancer Immunotherapy Using Biodegradable Mesoporous Silica Nanoparticles. doi.org/10.1002/adtp.202000130, 2020, Advanced TherapeuticsLink PDF

84. Kuai R*, Singh PB*, Sun X*, Xu C, Najafabadi Hassani A, Scheetz L, Yuan W, Xu Y, Hong H, Keskin DB, Wu CJ, Jain R, Schwendeman A§, Moon JJ§. Robust Anti‐Tumor T Cell Response with Efficient Intratumoral Infiltration by Nanodisc Cancer Immunotherapy. doi: 10.1002/adtp.202000094, 2020, Advanced TherapeuticsLink PDF

83. Habibi N, Christau S, Ochyl LJ, Fan Z, Hassani Najafabadi A, Kuehnhammer M, Zhang M, Helgeson M, von Klitzing R, Moon JJ, Lahann J. Engineered Ovalbumin Nanoparticles for Cancer Immunotherapy. doi.org/10.1002/adtp.202000100, 2020, Advanced TherapeuticsLink PDF

82. Scheetz L*, Kadiyala P*, Sun X*, Son S, Najafabadi AH, Aikins, M, Lowenstein PR, Schwendeman A§, Castro MG§, Moon JJ§. Synthetic high-density lipoprotein nanodiscs for personalized immunotherapy against gliomas. doi: 10.1158/1078-0432.CCR-20-0341, 2020, Clinical Cancer ResearchLink PDF

81. Scheetz L, Yu M, Li D, Castro MG, Moon JJ§, Schwendeman A§. Synthetic HDL Nanoparticles Delivering Docetaxel and CpG for Chemoimmunotherapy of Colon Adenocarcinoma. 21, 5, 1777, 2020, Int. J. Mol. Sci. Link PDF

80. Okeke EB, Louttit C, Fry C, Najafabadi AH, Han K, Nemzek J§, Moon JJ§. Inhibition of neutrophil elastase prevents neutrophil extracellular trap formation and rescues mice from endotoxic shock. 238, 119836, 2020, BiomaterialsLink PDF

79. Son S*, Nam J*, Zenkov I, Ochyl LJ, Xu Y, Scheetz L, Shi J, Farokhzad OC§, Moon JJ§. Sugar-Nanocapsules Imprinted with Microbial Molecular Patterns for mRNA Vaccination. doi: 10.1021/acs.nanolett.9b03483, 2020, Nano Letters. Link PDF

78. Garcia-Fabiani MB, Ventosa M, Comba A, Candolfi M, Nicola Candia AJ, Alghamri M, Kadiyala P, Carney S, Faisal SM, Schwendeman A, Moon JJ, Scheetz L, Lahann J, Mauser A, Lowenstein PR, Castro MG. Immunotherapy for gliomas: shedding light on progress in preclinical and clinical development.  doi: 10.1080/13543784.2020.1768528, 2020, Expert Opin Investig Drugs. Link PDF

77. Draijer C, Speth JM, Penke LRK, Zaslona Z, Bazzill JD, Lugogo N, Huang YJ, Moon JJ, Peters-Golden M. Resident alveolar macrophage-derived vesicular SOCS3 dampens allergic airway inflammation. doi: 10.1096/fj.201903089R, 2020, FASEB J. Link PDF

76. Altshuler DB, Kadiyala P, Nuñez FJ, Nuñez FM, Carney S, Alghamri MS, Garcia-Fabiani MB, Asad AS, Nicola Candia AJ, Candolfi M, Lahann J, Moon JJ, Schwendeman A, Lowenstein PR, Castro MG. Prospects of biological and synthetic pharmacotherapies for glioblastoma. doi: 10.1080/14712598.2020.1713085, 2020, Expert Opin Biol Ther. Link PDF

2019

75. Xu C, Nam J, Hong H, Xu Y, Moon JJ. Positron Emission Tomography-Guided Photodynamic Therapy with Biodegradable Mesoporous Silica Nanoparticles for Personalized Cancer Immunotherapy. 13, 10, 12148-12161, 2019, ACS Nano. Link PDF

74. Bose RJ, Kim M, Chang JH, Paulmurugan R, Moon JJ, Koh WG, Lee SH, Park H. Biodegradable polymers for modern vaccine development. 77, 12-24, 2019, J. Industrial and Engineering ChemistryLink PDF

73. Fan Y, Stronsky SM, Xu Y, Steffens JT, van Tongeren SA, Erwin A, Cooper CL*, Moon JJ*. Multilamellar Vaccine Particle Elicits Potent Immune Activation with Protein Antigens and Protects Mice against Ebola Virus Infection. 13, 10, 11087-11096, 2019, ACS Nano. Link PDF

72. Lee Y, Sugihara K, Gillilland MG 3rd, Jon S, Kamada N, Moon JJ. Hyaluronic acid-bilirubin nanomedicine for targeted modulation of dysregulated intestinal barrier, microbiome, and immune responses in colitis. 19, 1, 118-126, 2020, Nature Materials. Link PDF
** Featured by Nature Materials Link PDFNew England Journal of Medicine Link

71. Nam J*, Son S*, Park C, Zou W, Shea L, Moon JJ. Cancer nanomedicine for combination cancer immunotherapy. 4, 398-414, 2019, Nature Reviews Materials.  Link PDF

70. Scheetz L*, Park KS*, Li Q, Lowenstein PR, Castro MG, Schwendeman A, Moon JJ. Engineering strategies for personalized cancer immunotherapy: a paradigm shift. 3, 10, 768-782, 2019, Nature Biomedical Engineering. Link PDF

69. Louttit C*, Park KS*, Moon JJ. Bioinspired nucleic acid structures for immune modulation. 217, 119287, 2019, Biomaterials. Link PDF

68. Chen Z, Wholey WY, Hassani Najafabadi A, Moon JJ, Grigorova I, Chackerian B, Cheng W. Self-Antigens Displayed on Liposomal Nanoparticles above a Threshold of Epitope Density Elicit Class-Switched Autoreactive Antibodies Independent of T Cell Help. 1801677, 2019, J Immunology. Link PDF

67. Speth JM, Penke LR, Bazzill JDPark KS, de Rubio RG, Schneider DJ, Ouchi H, Moon JJ, Keshamouni VG, Zemans RL, Lama VN, Arenberg DA, Peters-Golden M. Alveolar macrophage secretion of vesicular SOCS3 represents a platform for lung cancer therapeutics. 4, 20, 131340, 2019, JCI Insight. Link PDF

66. Weerappuli PD*, Louttit C*, Kojima T, Brennan L*, Yalavarthi S, Xu Y, Ochyl JL, Maeda ML, Kim HS, Knight JS, Takayama S§, Moon JJ§. Extracellular trap-mimicking DNA-histone mesostructures synergistically activate dendritic cells. 8, 22, e1900926, 2019, Advanced Healthcare Materials. Link PDF

65. Lee Y, Arai Y, Ahn J, Kim D, Oh S, Kang D, Lee H, Moon JJ, Choi B, Lee SH. Three-dimensional microenvironmental priming of human mesenchymal stem cells in hydrogels facilitates efficient and rapid retroviral gene transduction via accelerated cell cycle synchronization. 11, 27, 2019, NPG Asia MaterialsLink PDF

64. Wang T, Subramanian C, Yu M, White P, Kuai R, Sanchez J, Moon JJ, Timmermann BM, Schwendeman A, Cohen MS. Mimetic sHDL nanoparticles: A novel drug-delivery strategy to target triple-negative breast cancer. 166, 6, 1168-1175, 2019, SurgeryLink PDF

63. Song Y, Kadiyala U, Weerappuli P, Valdez JJ, Yalavarthi S, Louttit C, Knight JS, Moon JJ, Weiss DS, VanEpps JS, and Takayama S. Antimicrobial Microwebs of DNA-Histone Inspired from Neutrophil Extracellular Traps. 31, 1807436, 2019, Advanced Materials.  Link PDF

62. Kadiyala P, Li D, Nuñez FM, Altshuler D, Doherty R, Kuai R, Yu M, Kamran N, Edwards M, Moon JJ, Lowenstein PR, Castro MG, and Schwendeman A. High-Density Lipoprotein-Mimicking Nanodiscs for Chemo-immunotherapy against Glioblastoma Multiforme. 13, 2, 1365-1384, 2019, ACS Nano.  Link PDF

61. Lee B, Ahn SY, Park CMoon JJ, Lee JH, Luo D, Um SH, and Shin SW. Revealing the Presence of a Symbolic Sequence Representing Multiple Nucleotides Based on K-Means Clustering of Oligonucleotides. 24, 4, 348, 2019, Molecules.  Link PDF
2018

60. Bazzill JD, Ochyl LJ, Giang E, Castillo S, Law M*, and Moon JJ*. Interrogation of antigen display on individual vaccine nanoparticles for achieving neutralizing antibody responses against hepatitis C virus. doi: 10.1021/acs.nanolett.8b03601, 2018, Nano Letters. Link PDF

59. Ochyl LJ, and Moon JJ. Dendritic cell membrane vesicles for activation and maintenance of antigen‐specific T cells. http://doi.org/10.1002/adhm.201801091, 2018, Advanced Healthcare MaterialsLink PDF

58. Bazzill JD*, Stronsky SM*, Kalinyak LC, Ochyl LJ, Steffens JT, van Tongeren SA, Cooper CL*, Moon JJ*. Vaccine nanoparticles displaying recombinant Ebola virus glycoprotein for induction of potent antibody and polyfunctional T cell responses. doi: 10.1016/j.nano.2018.11.005., 2018, NanomedicineLink PDF

57. Ochyl LJ, Bazzill JD, Park C, Xu Y, Kuai R, and Moon JJ. PEGylated tumor cell membrane vesicles as a new vaccine platform for cancer immunotherapy. 182, 157-166, 2018, BiomaterialsLink PDF

56. Liu Z, Jiang W, Nam J, Moon JJ, and Kim BYS. Immunomodulating Nanomedicine for Cancer Therapy. 18, 11, 6655-6659, 2018, Nano LettersLink PDF

55. Bose RJ, Kim BJ, Arai Y, Han IB, Moon JJ, Paulmurugan R, Park H, and Lee SH. Bioengineered stem cell membrane functionalized nanocarriers for therapeutic targeting of severe hindlimb ischemia. 185, 360-370, 2018, BiomaterialsLink  PDF

54. Moon JJ, Schwendeman SP, Schwendeman A. Nanomedicine: past, present, and future. 130, 1-2, 2018, Adv. Drug. Deliv. Rev. (EditorialLink PDF

53. Mazzara JM, Ochyl LJ, Hong JKY, Moon JJ, Prausnitz MR, Schwendeman SP. Self-healing Encapsulation and Controlled Release of Vaccine Antigens from PLGA Microparticles and Microneedles. http://doi.org/10.1002/btm2.10103. 2018, Bioengineering & Translational Medicine. Link PDF

52. Subramanian C, White PT, Kuai R, Kalidindi A, Castle VP, Moon JJ, Timmermann BN, Schwendeman A, and Cohen MS. Synthetic high-density lipoprotein nanoconjugate targets neuroblastoma stem cells, blocking migration and self-renewal, doi: 10.1016/j.surg.2018.01.023, 2018, SurgeryLink PDF

51. Kuai R, Sun X, Yuan W, Ochyl LJ, Xu Y, Hassani Najafabadi A, Scheetz L, Yu MZ, Balwani I, Schwendeman A*, and Moon JJ*. Dual TLR agonist nanodiscs as a strong adjuvant system for vaccines and immunotherapy. 282, 131-139, 2018, J Control Release. Link PDF

50. Moon JJ, Hennink WE, Schwendeman SP, Schwendeman A. NanoDDS 2017: The 15th International Nanomedicine & Drug Delivery Symposium. 282, 1-2, 2018, J Control Release (Editorial). Link PDF

49. Kuai R*, Yuan W*, Xu Y, Fan Y, Schwendeman A, Moon JJ. Elimination of established tumors with nanodisc-based combination chemoimmunotherapy. 4,4, eaao1736, 2018, Science Advances. Link PDF

48. Nam J*, Son S*, Ochyl LJ, Kuai R, Schwendeman A, and Moon JJ. Chemo-photothermal therapy combination elicits anti-tumor immunity against advanced metastatic cancer. 9, 1, 1074, 2018, Nature Communications. Link PDF

47. Xu C, Chen F, Valdovinos HF, Jiang D, Goel S, Yu B, Sun H, Barnhart TE, Moon JJ, Cai W. Bacteria-like mesoporous silica-coated gold nanorods for positron emission tomography and photoacoustic imaging-guided chemo-photothermal combined therapy. 165, 56-65, 2018, BiomaterialsLink PDF

46. Park HJ*, Kuai R*, Jeon EJ, Seo Y, Jung Y, Moon JJ, Schwendeman A, Cho SW. High-density lipoprotein-mimicking nanodiscs carrying peptide for enhanced therapeutic angiogenesis in diabetic hindlimb ischemia. doi: 10.1016/j.biomaterials.2018.01.027, 2018, BiomaterialsLink PDF

45. Kuai R, Sun X, Yuan W, Xu Y, Schwendeman A, Moon JJ. Subcutaneous Nanodisc Vaccination with Neoantigens for Combination Cancer Immunotherapy. 2018 doi: 10.1021/acs.bioconjchem.7b00761, 2018, Bioconjug ChemLink PDF

44. Chen Z, Moon JJ, Cheng W. Quantitation and stability of protein conjugation on liposomes for controlled density of surface epitopes. doi: 10.1021/acs.bioconjchem.8b00033, 2018, Bioconjug Chem. Link PDF

43. Bose RJ, Paulmurugan R, Moon J, Lee SH, Park H. Cell membrane-coated nanocarriers: the emerging targeted delivery system for cancer theranostics. doi: 10.1016/j.drudis.2018.02.001, 2018, Drug Discov TodayLink PDF

42. Guo Y, Yuan W, Yu B, Kuai R, Hu W, Morin EE, Garcia-Barrio MT, Zhang J, Moon JJ, Schwendeman A, Eugene Chen Y. Synthetic High-Density Lipoprotein-Mediated Targeted Delivery of Liver X Receptors Agonist Promotes Atherosclerosis Regression. doi: 10.1016/j.ebiom.2017.12.021, 2018, EBioMedicine. Link PDF

2017

41. Fan Y, Kuai R, Xu Y, Ochyl LJ, Irvine DJ, and Moon JJ. Immunogenic cell death amplified by co-localized adjuvant delivery for cancer immunotherapy. 17(12):7387-739, 2017, Nano LettersLink PDF

40. Kuai R, Subramanian C, White P, Moon JJ, Cohen MS, Schwendeman A. Synthetic high-density lipoproteins for targeted delivery of withalongolides to treat adrenocortical carcinoma, 12, 6581, 2017, Int. J. Nanomedicine. Link PDF

39. Nam J, Son S, Moon JJ. Adjuvant-loaded spiky gold nanoparticles for activation of innate immune cells, DOI: 10.1007/s12195-017-0505-8, 2017, Cellular and Molecular BioengineeringLink PDF

38. Bailey BA, Desai KG, Ochyl LJ, Ciotti SM, Moon JJ, Schwendeman SP. Self-encapsulating poly(lactic-co-glycolic acid) (PLGA) microspheres for intranasal vaccine delivery, DOI: 10.1021/acs.molpharmaceut.7b00586, 2017, Molecular PharmaceuticsLink PDF

37. Tang J, Kuai R, Yuan W, Drake L, Moon JJ, Schwendeman A. Effect of size and PEGylation of liposomes and peptide-based synthetic lipoproteins on tumor targeting. 13, 1869-78, 2017, Nanomedicine. Link PDF

36. Kuai R, Ochyl LJ, Bahjat KS, Schwendeman A* and Moon JJ*. Designer vaccine nanodiscs for personalized cancer immunotherapy. 16, 4, 489-496, 2017, Nature Materials. Link PDF
** Featured by Nature World News, Science Alert, Fierce Biotech, Yahoo! News, R&D, eCancer, Medical Physics Web, Nanotechweb, Technology Networks, Technology.org, C2W.nl, La Stampa, Scientias, Controlled Environments, Tech Times, STRF.ru, Business Standard, CanIndia, La Razon, Health Canal, E! Informador, My Science, Azonano, Nanowerk, Health Medicine, The Medical News, Health Medicinet  Link

35. Bailey BA, Ochyl LJ, Schwendeman SP, and Moon JJ. Towards a single dose vaccination strategy with self-encapsulating PLGA microspheres. doi: 10.1002/adhm.201601418, 2017, Advanced Healthcare Materials. (most read article of the month) Link PDF
** Featured by Advanced Science News

34. Gao J, Ochyl LJ, Yang E, and Moon JJ. Cationic liposomes promote antigen cross-presentation in dendritic cells by alkalizing the lysosomal pH and limiting degradation of antigens. 12, 1251-64, 2017, International J. NanomedicineLink PDF

33. Aikins M, Bazzill J, and Moon JJ. Vaccine nanoparticles for protection against HIV infection. 12, 6, 673-782, 2017, Nanomedicine (Lond). Link PDF

2016

32. Fan Y and Moon JJ. Particulate delivery systems for vaccination against bioterrorism agents and emerging infectious pathogens, doi:10.1002/wnan.1403. 2016, WIREs Nanomedicine & Nanobiotechnology(selected as the cover & one of the Top 10 most accessed articles in 2016) Link PDF
** Featured by Materials Views, Nanotechnology Now, Today Topics, and Phys.org

31. Kuai R, Li D, Chen YE, Moon JJ, and Schwendeman A. High density lipoproteins: nature’s multifunctional nanoparticles, 10, 3, 3015-41, 2016, ACS NanoLink PDF

30. Subramanian C, Kuai R, Zhu Q, White P, Moon JJ, Schwendeman A, and Cohen MS. Synthetic high-density lipoprotein nanoparticles: a novel therapeutic strategy for adrenocortical carcinomas, 159, 1, 284-95, 2016, SurgeryLink PDF

29. Kuai R*, Ochyl LJ*, Schwendeman A, and Moon JJ. Lipid-based nanoparticles for vaccine applications. Book chapter in Biomedical Engineering: Frontier Research and Converging Technologies. Edited by Drs. Jo, Jun, Shin, and Lee, Springer, 9, 177-197, 2016.  (PEER-REVIEWED BOOK CHAPTER) Link

2015

28. Fan Y and Moon JJ. Nanoparticle vaccine delivery systems designed to improve cancer vaccines and immunotherapy, 3, 662-685, 2015, Vaccines. Link PDF

27. Fan Y*, Sahdev P*, Ochyl LJ, Akerberg J, and Moon JJ. Cationic liposome-hyaluronic acid hybrid nanoparticles for intranasal vaccination with subunit antigens. 208, 121-9, 2015, J Control ReleaseLink PDF

26. Ochyl JL and Moon JJ. Whole-animal imaging and flow cytometric techniques for analysis of antigen-specific CD8+ T cell responses after nanoparticle vaccination, e52771, doi:10.3791/52771, 2015, JoVELink PDF

2014

25. Sahdev P, Ochyl JL, and Moon JJ. Biomaterials for nanoparticle vaccine delivery systems, 31, 2563-2582, 2014, Pharmaceutical ResearchLink PDF

2013

24. Li AV*, Moon JJ*, Abraham W, Elkhader J, Suh K, Yen M, Im EJ, Barouch DH, and Irvine DJ. Generation of robust effector memory T-cell-based mucosal and systemic immunity with pulmonary nanoparticle vaccination. 5, 204, 204ra130, 2013, Science Translational Medicine.  (selected as the cover) Link PDF
** Featured by Science News Daily, Chemistry Views, Newswise, Vaccine News, The Medical News, Medical News Today, Scicasts, MedicalXpress, LiveScience, Health Canal, and Nanowerk.

23. Kim M, Song L, Moon J, Sun ZY, Bershteyn A, Hanson M, Cain D, Goka S, Kelsoe G, Wagner G, Irvine D, Reinherz EL. Immunogenicity of membrane-bound HIV-1 gp41 MPER segments is dominated by residue accessibility and modulated by stereochemistry. 288, 44, 31888-901, 2013, J. Biol. Chem. Link PDF

2012

22. Demuth PC*, Moon JJ*, Suh H, Hammond PT, and Irvine DJ, and Huang B. Releasable layer-by-layer assembly of stabilized lipid nanocapsules on microneedles for enhanced transcutaneous vaccine delivery, 6, 8041-51, 2012, ACS Nano. Link PDF

21. Moon JJ, Huang B, and Irvine DJ. Engineering nano- and micro-particles to tune immunity, 24, 3724-462012, Advanced Materials. Link PDF

20. Moon JJ, Suh H, Li AV, Ockenhouse CF, Yadava A, and Irvine DJ. Enhancing humoral responses to a malaria antigen with nanoparticle vaccines that expand Tfh cells and promote germinal center induction, 109, 1080-52012, PNAS. Link PDF
** Featured by PNAS: Commentary, 109, 999-1000, 2012. Link PDF

19. Moon JJ, Suh H, Polhemus ME, Ockenhouse CF, Yadava A, and Irvine DJ. Antigen-displaying lipid-enveloped PLGA nanoparticles as delivery agent for Plasmodium vivax malaria vaccine, 7, e314722012, PLoS One. Link PDF

2011

18. Moon JJ, Suh H, Bershteyn A, Stephan MT, Liu H, Huang B, Sohail M, Luo S, Um SH, Chiu W, and Irvine DJ. Interbilayer-crosslinked multilamellar vesicles for potent humoral and cellular immune responses, 10, 243-251, 2011, Nature Materials. Link PDF
** Featured by Nature Materials: News and Views, 10, 166-68, 2011, and Nature Biotech: Research Highlights, 29, 330, 2011. Link PDF

17. Bershteyn A, Hanson MC, Crespo MP, Moon JJ, Li AV, Suh H, and Irvine DJ. Robust IgG responses to nanograms of antigen using a biomimetic lipid-coated particle vaccine, 157, 354-65, 2011, Journal of Controlled Release. Link PDF

2010

16. Stephan MT, Moon JJ, Um SH, Bershteyn A, and Irvine DJ. Therapeutic cell engineering with surface-conjugated synthetic nanoparticles, 16, 1035-41, 2010, Nature Medicine. Link PDF

15. Moon JJ, Saik JE, Poche RA, Leslie-Barbick JE, Lee SH, Smith AA, Dickinson ME, and West JL. Biomimetic hydrogels with pro-angiogenic properties, 31, 3840-3847, 2010, Biomaterials. Link PDF

2009

14. Hu Y, Atukorale PU, Lu JJ, Moon JJ, Um SH, Cho EC, Wang Y, Chen J, and Irvine DJ. Cytosolic delivery mediated via electrostatic surface binding of protein, virus, or siRNA cargos to pH-responsive core-shell gel particles, 10, 756-765, 2009, Biomacromolecules. Link PDF

13. Moon JJ, Hahn MS, Kim I, Nsiah BA, and West JL. Micropatterning of poly(ethylene glycol) diacrylate hydrogels with biomolecules to regulate and guide endothelial morphogenesis, 15, 579-585, 2009, Tissue engineering – Part A. Link PDF

12. Leslie-Barbick JE, Moon JJ, and West JL. Covalently-Immobilized Vascular Endothelial Growth Factor Promotes Endothelial Cell Tubulogenesis in Poly(ethylene glycol) Diacrylate Hydrogels, 20, 1763-1779, 2009, Journal of biomaterials science – Polymer Edition Link PDF

2008

11. Moon JJ, and West JL. Vascularization of engineered tissues: approaches to promote angiogenesis in biomaterials, 8, 300-310, 2008, Current topics in medicinal chemistry. Link PDF

10. Lee SH*, Moon JJ*, and West JL. Three-dimensional micropatterning of bioactive hydrogels via two-photon laser scanning photolithography for guided 3D cell migration, 29, 2962-2968, 2008, Biomaterials. * Authors contributed equally. Link PDF

9. Gobin AM*, Moon JJ*, and West JL. EphrinA I-targeted nanoshells for photothermal ablation of prostate cancer cells, 3, 351-358, 2008, International journal of nanomedicine.  Link PDF

2007

8. Moon JJ, Lee SH, and West JL. Synthetic biomimetic hydrogels incorporated with ephrin-A1 for therapeutic angiogenesis, 8, 42-49, 2007, Biomacromolecules. Link PDF

7. Lee SH, Moon JJ, Miller JS, and West JL. Poly(ethylene glycol) hydrogels conjugated with a collagenase-sensitive fluorogenic substrate to visualize collagenase activity during three-dimensional cell migration, 28, 3163-3170, 2007, Biomaterials. Link PDF

2006

6. Hahn MS, Taite LJ, Moon JJ, Rowland MC, Ruffino KA, and West JL. Photolithographic patterning of polyethylene glycol hydrogels, 27, 2519-2524, 2006, Biomaterials. Link PDF

5. Lee P, Lin R, Moon J, and Lee LP. Microfluidic alignment of collagen fibers for in vitro cell culture, 8, 35-41, 2006, Biomedical microdevices. Link PDF

2005

4. DeLong SA, Moon JJ, and West JL. Covalently immobilized gradients of bFGF on hydrogel scaffolds for directed cell migration, 26, 3227-3234, 2005, Biomaterials. Link PDF

3. Lee SH, Miller JS, Moon JJ, and West JL. Proteolytically degradable hydrogels with a fluorogenic substrate for studies of cellular proteolytic activity and migration, 21, 1736-1741, 2005, Biotechnology Progress Link PDF

2. Moon JJ, Matsumoto M, Patel S, Lee L, Guan JL, and Li S. Role of cell surface heparan sulfate proteoglycans in endothelial cell migration and mechanotransduction, 203, 166-176, 2005, J Cell Physiol. (selected as a cover) Link PDF

2003

1. Li S, Moon JJ, Miao H, Jin G, Chen BP, Yuan S, Hu Y, Usami S, and Chien S. Signal transduction in matrix contraction and the migration of vascular smooth muscle cells in three-dimensional matrix, 40, 378-388, 2003, J Vasc Res. Link PDF